Turkey Tetrazzini recipe (with cream of mushroom soup)

This Healthy Turkey Tetrazzini recipe (with cream of mushroom soup) is old fashioned comfort food that's easy to make and great for using up leftover spaghetti noodles and/or leftover turkey!

This healthy Turkey Tetrazzini with cream of mushroom soup is most popular during the colder months and when you have leftover Thanksgiving turkey. This recipe was inspired by my Easy Turkey Pot Pie (with cream of chicken soup) on this site, and pairs well with Italian Breadsticks or Garlic Bread.

🥘Ingredient Notes

For this turkey casserole, you don't need heavy cream or cream cheese to get a creamy sauce.

Made with simple ingredients like chunks of turkey, spaghetti noodles, and frozen mixed vegetables, you'll find you have most (if not all) of the ingredients on hand. For this healthier version, you'll need the following ingredients:

• Mushrooms: Using fresh mushrooms is critical to this recipe, as well as cooking them with the butter and onion
• 10 oz can of condensed cream of mushroom soup *see TOP TIP
• Milk- I use 1%

📖Variations & Substitutions

• Noodles - you can use any type of noodles such as thin spaghetti (spaghettini) angel hair pasta, or fettuccine. You could also use whole wheat spaghetti noodles or a lighter WW noodle (see WW points section)
• Turkey - you could use leftover turkey, turkey breast, ground turkey, chicken breast, or rotisserie chicken.
• Cheese- you can use cheddar cheese or Monterey jack cheese instead.
• Add-ins - you can add bell pepper if you like.

🔪How to make Turkey Tetrazzini with Cream of Mushroom Soup

Prep: Preheat oven to 375°F (190 degrees C). If you are not using leftover spaghetti noodles, cook spaghetti according to package directions (al dente) and drain. Cook turkey and chop into bite-sized pieces (if not using cooked leftover turkey). Spray a 3-quart casserole dish with non-stick cooking spray.

Mix mushrooms, onions, butter and salt together in a medium bowl.

Cook for 5 minutes in the microwave.

Transfer cooked noodles, mushrooms, butter and onion to a large bowl and stir in remainder of ingredients (except mozzarella cheese)

Transfer into prepared casserole dish

Add grated mozzarella cheese.

Bake, uncovered, until heated through, 30-35 minutes until mushrooms and onions are cooked.

Turn up to 500 degrees F/260 degrees C (broil) for 2 minutes until cheese is bubbly and lightly browned. Keep a close eye on it so it doesn't burn.

If desired, sprinkle with fresh parsley.

🥗 What to serve with Turkey Tetrazzini

This turkey casserole pairs perfectly with a simple garlic bread (from baguette). But it also goes well with Bread Machine Breadsticks (shown), Cloud Bread, Old Fashioned Buns, and Onion and Olive Bread.

🌡️Storage

Store leftover turkey tetrazzini in an airtight container in the fridge for up to 3 days. If you are just storing a small amount or storing it overnight, you can cover it in plastic wrap.

This recipe freezes well in a sealed container and can be frozen for up to 3 months.

To Reheat:

Defrost it in the fridge overnight, then microwave it until warm.

You can also reheat it in the oven:

I love using this casserole reheating technique for any pasta casserole- it prevents the casserole from drying out.

1. Simply bring it out of the freezer the night before and let it defrost (preferably in the fridge). Ideally, you want to keep it at room temperature for about 30 minutes to an hour before you put it in the oven.
2. Then heat the oven to 350 degrees F/175 degrees C, remove the lid and plastic wrap, then tightly seal your casserole dish with aluminum foil (shiny side in) and put it in the oven for 20 - 30 minutes, until it's warmed through. *you can remove the foil and broil it for the final 2 minutes if you desire.
3. You can use an instant read thermometer (affiliate link) to make sure it's done (165 degrees F/75 degrees C)

👪 Serving Size

This easy turkey tetrazzini recipe makes 10 servings @ a little over a cup per serving. However, you can half, double, or triple the recipe by clicking on the serving number and selecting the number of servings you'd like. The ingredient quantities will automatically adjust.

🔢WW Points

This turkey tetrazzini casserole, as is, is 10 WW points per serving. You can lower the points to 7 ww points by using low-fat cream of mushroom soup, fat-free parmesan cheese, light butter, and a lower-point noodle (such as Fiber gourmet light spaghetti, shredded spaghetti, or miracle noodles ) instead. *I calculated it on the WW app recipe builder using Fiber Gourmet light spaghetti.

❔ Recipe FAQ's